The game is almost entirely mouse, rather than keyboard, controlled.
Navigation through the game's screens is done via the toolbar at the bottom of the screen. Some of the buttons can be safely ignored by a beginneer (eg, the stock market, or the banking screen, both accessed via the mobile phone button on the port screen) Right click in order to return to the previous screen.
When you're in port and looking at the world map, click on a port twice in order to get your ship to sail there. Click on a port once to see that port's principle imports and exports.
Hope I helped. Post again if I missed something you'd like to know.
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